Trifluoroacetic acid → HCID 59366526, compound

HRID 908656Notes

Reaction equation

HRID 908656 reaction equation
[Cl:1][C:2]([Cl:23])=[CH:3][CH2:4][O:5][C:6]1[CH:20]=[C:19]([Cl:21])[C:9]([O:10][CH2:11][C:12]([O:14]C(C)(C)C)=[O:13])=[C:8]([Cl:22])[CH:7]=1.FC(F)(F)C(O)=O>C(Cl)Cl>[Cl:23][C:2]([Cl:1])=[CH:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([Cl:22])[C:9]([O:10][CH2:11][C:12]([OH:14])=[O:13])=[C:19]([Cl:21])[CH:20]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 59366522Tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate

Product 1

HCID 59366526HCID 59366526, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Conditions

Temperature
0 °C

Procedure

A mixture of 0.3 gram (0.0008 mole) of tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate in 3.0 mL of methylene chloride was stirred and cooled to 0° C. Trifluoroacetic acid (3.0 mL, 0.04 mole) was added and the reaction mixture was allowed to warm to ambient temperature where it stirred for two hours. The reaction mixture was concentrated under reduced pressure leaving a residue. The residue was dissolved in methylene chloride and the solution concentrated under reduced pressure and the resulting residue was dissolved in methylene chloride again. The solution was concentrated under reduced pressure to yield a quantitative amount of the subject compound as a white powder.

Workup

  1. temperatureto warm to ambient temperature where it
  2. stirringstirred for two hours
  3. concentrationThe reaction mixture was concentrated under reduced pressure
  4. customleaving a residue
  5. concentrationthe solution concentrated under reduced pressure
  6. dissolutionthe resulting residue was dissolved in methylene chloride again
  7. concentrationThe solution was concentrated under reduced pressure

Sources & evidence

ORD record
ord-7c60a271ea024946a3ffb269a31a06e4
Source dataset
uspto-grants-2011_09
Patent number
US08017635B2

Reaction notes

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