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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 908903Generated: October 31, 2026

Potassium Hydroxide → HCID 23150782, compound

https://huagongshe.com/reaction/908903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant1-(3-chloropropyl)pyrrolidine HydrochlorideHCID 11571916—
ReactantHCID 23150777HCID 23150777—
ProductHCID 23150782HCID 2315078223.6%

Reaction Steps

Following the procedure described in example 2, but starting from trans-3-(4-fluoro-3-methylphenyl)prop-2-en-1-ol (710 mg), potassium hydroxide (592 mg, 85% wt) and 1-(3-chloropropyl)pyrrolidine, hydrochloride (802 mg) in dimethylsufoxide (6 mL) affords 280 mg of trans-1-{3-[3-(4-fluoro-3-methylphenyl)allyloxy]propyl}-pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08017646B2
Source datasetuspto-grants-2011_09
ORD IDord-67b4fa7674334dec8994a411b1c2699b
Source noteuspto-grants-2011_09