Chlorotrimethylsilane → HCID 11720208, compound

Participants

Reaction Steps

2-[2-(4-Dimethylamino-4-phenylcyclohexylidene)acetylamino]-3-(1H-indol-3-yl)propanoic acid methyl ester (142 mg, 0.3 mmol) was dissolved in ethyl methyl ketone (9 ml), and chlorotrimethylsilane (0.055 ml, 0.43 mmol) was added. After 2 h it was possible to obtain the product as a colourless compound in a yield of 50 mg (15%) with an m.p. of 164-168° C.

Provenance & Evidence