反应详情

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-(1H-indol-3-ylmethyl)acetamide (120 mg, 0.309 mmol) was dissolved in ethyl methyl ketone (5 ml), and chlorotrimethylsilane (0.058 ml, 0.46 mmol) was added. After 1.5 h the hydrochloride was isolated with an m.p. of 173-185° C. in a yield of 63% (82 mg).