反应详情

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-[4-(1H-indol-3-yl)butyl]acetamide (184 mg, 0.428 mmol) was dissolved in ethyl methyl ketone (10 ml), and chlorotrimethylsilane (0.08 ml, 0.64 mmol) was added. After 1.5 h the hydrochloride was isolated as a colourless solid with an m.p. of 185-188° C. in a yield of 74% (147 mg).