反应详情

Palladium-on-charcoal (5%, 90 mg) was added to a solution of (4-dimethylamino-4-phenylcyclohexylidene)acetic acid methyl ester hydrochloride (1.79 g, 5.77 mmol) in methanol. The reaction mixture was hydrogenated at RT under a pressure of 3 bar for 5 h. The catalyst was separated off over Celite and the filtrate was concentrated. The product was thereby isolated as a colourless, oily compound in a quantitative yield (1.79 g).

1. customThe catalyst was separated off over Celite
2. concentrationthe filtrate was concentrated
3. customThe product was thereby isolated as a colourless, oily compound in a quantitative yield (1.79 g)