(4-Dimethylamino-4-phenylcyclohexylidene)acetic acid methyl ester hydrochloride → (4-Dimethylamino-4-phenylcyclohexyl)acetic acid methyl ester hydrochloride

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반응 단계

Palladium-on-charcoal (5%, 90 mg) was added to a solution of (4-dimethylamino-4-phenylcyclohexylidene)acetic acid methyl ester hydrochloride (1.79 g, 5.77 mmol) in methanol. The reaction mixture was hydrogenated at RT under a pressure of 3 bar for 5 h. The catalyst was separated off over Celite and the filtrate was concentrated. The product was thereby isolated as a colourless, oily compound in a quantitative yield (1.79 g).

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