反应详情

2-(4-Dimethylamino-4-phenylcyclohexyl)-N-phenethylacetamide (220 mg, 0.6 mmol) was dissolved in ethyl methyl ketone with gentle heating and chlorotrimethylsilane (0.113 ml, 0.9 mmol) was added. After 1.5 h it was possible to isolate a colourless, hygroscopic solid in a yield of 80% (191 mg).

1. temperaturewith gentle heating
2. customto isolate a colourless, hygroscopic solid in a yield of 80% (191 mg)