HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 11589419, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | HCID 11589420 | HCID 11589420 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 11589419 | HCID 11589419 | 80% |
Reaction Steps
2-(4-Dimethylamino-4-phenylcyclohexyl)-N-phenethylacetamide (220 mg, 0.6 mmol) was dissolved in ethyl methyl ketone with gentle heating and chlorotrimethylsilane (0.113 ml, 0.9 mmol) was added. After 1.5 h it was possible to isolate a colourless, hygroscopic solid in a yield of 80% (191 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017630B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-534ef5d025ff41ce9cd6fc33d7449a80 |
| Source note | uspto-grants-2011_09 |