反应详情

2-(4-Dimethylamino-4-phenylcyclohexyl)-N-[6-(1H-indol-3-yl)hexyl]acetamide (516 mg, 1.12 mmol) was dissolved in a mixture of ethyl methyl ketone (25 ml) and ethanol (5 ml), and 5 M isopropanolic hydrochloric acid (0.44 ml, 2.2 mmol) was added. After 3 h the reaction mixture was concentrated, ether (15 ml) was added and the mixture was concentrated again. The residue was digested with ether (30 ml). After filtration, the product was obtained as a beige-coloured solid in a yield of 62% (342 mg).

1. additionwas added
2. concentrationAfter 3 h the reaction mixture was concentrated
3. additionether (15 ml) was added
4. concentrationthe mixture was concentrated again
5. filtrationAfter filtration
6. customthe product was obtained as a beige-coloured solid in a yield of 62% (342 mg)