Water → HCID 11711119, compound

Participants

Reaction Steps

Chlorotrimethylsilane (0.097 ml) and water (7 μl) were added to a solution of the less polar diastereoisomer of 2-(4-dimethylamino-4-phenyl-cyclohexyl)-N-(4-methoxy-phenyl)-acetamide (255 mg, 0.7 mmol) in ethyl methyl ketone (2 ml). The hydrochloride was extracted as an oil with hexane and isolated in a quantitative yield.

Provenance & Evidence