HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 909258Generated: November 1, 2026
Hydrochloric Acid → HCID 178456373, compound
https://huagongshe.com/reaction/909258
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178456374 | HCID 178456374 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178456373 | HCID 178456373 | — |
Reaction Steps
A mixture of 4.56 g (12 mmol) [trans-4-(4-isopropyl-piperazine-1-carbonyl)-cyclohexyl]-carbamic acid tert-butyl ester and 29 mL 4N HCl in dioxane was stirred for 6 h at 50° C. evaporated to dryness and used without further purification in the subsequent step. MS (m/e): 254.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08017773B2 |
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| Source dataset | uspto-grants-2011_09 |
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| ORD ID | ord-cc071450fa2540b0a2b9884ec074b78e |
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| Source note | uspto-grants-2011_09 |
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