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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 909258Generated: November 1, 2026

Hydrochloric Acid → HCID 178456373, compound

https://huagongshe.com/reaction/909258

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178456374HCID 178456374—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178456373HCID 178456373—

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of 4.56 g (12 mmol) [trans-4-(4-isopropyl-piperazine-1-carbonyl)-cyclohexyl]-carbamic acid tert-butyl ester and 29 mL 4N HCl in dioxane was stirred for 6 h at 50° C. evaporated to dryness and used without further purification in the subsequent step. MS (m/e): 254.1 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08017773B2
Source datasetuspto-grants-2011_09
ORD IDord-cc071450fa2540b0a2b9884ec074b78e
Source noteuspto-grants-2011_09