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HRID909258

反应详情

EQUATION

反应方程式

HRID 909258 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)N1CCN(C(=O)[C@H]2CC[C@H](NC(=O)OC(C)(C)C)CC2)CC1
HCID178456374

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCN(C(=O)[C@H]2CC[C@H](N)CC2)CC1.Cl.Cl
HCID178456373

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

CONDITIONS

反应条件

温度
50 °C

PROCEDURE

实验过程

A mixture of 4.56 g (12 mmol) [trans-4-(4-isopropyl-piperazine-1-carbonyl)-cyclohexyl]-carbamic acid tert-butyl ester and 29 mL 4N HCl in dioxane was stirred for 6 h at 50° C. evaporated to dryness and used without further purification in the subsequent step. MS (m/e): 254.1 (MH+).

WORKUP

后处理

  1. customevaporated to dryness
  2. customused without further purification in the subsequent step