Chloroform → 4-oxo-2-phenyl-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-7-carbonitrile

HRID 90949Notes

Reaction equation

HRID 90949 reaction equation
[CH:29]([Cl:30])([Cl:31])[Cl:32].[O:1]=[c:2]1[c:3]2[c:4]([n:5][c:6]3[n:7]1[cH:8][c:9]([C:12](=[O:13])[NH2:14])[cH:10][cH:11]3)[s:15][c:16](-[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[cH:17]2.[P:24]([Cl:25])([Cl:26])([Cl:27])=[O:28]>>[O:1]=[c:2]1[c:3]2[c:4]([n:5][c:6]3[n:7]1[cH:8][c:9]([C:12]#[N:14])[cH:10][cH:11]3)[s:15][c:16](-[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[cH:17]2

Participants

4

Reactant 3

HCID 6212ChloroformHCID 24813Phosphorus oxychlorideHCID 128623674-oxo-2-phenyl-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-7-carboxamide

Product 1

HCID 128623744-oxo-2-phenyl-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-7-carbonitrile

Sources & evidence

ORD record
ord-b8645624566e4b019198441688fb48eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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