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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 90983Generated: October 27, 2026

Pyridine → 2-(4-fluorotetrahydro-2H-pyran-4-yl)-2-hydroxyacetonitrile

https://huagongshe.com/reaction/90983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantEthyl AcetateHCID 8857—
ReactantHydrofluoric AcidHCID 14917—
Reactant1,6-Dioxaspiro[2.5]octane-2-carbonitrileHCID 21437903—
Product2-(4-fluorotetrahydro-2H-pyran-4-yl)-2-hydroxyacetonitrileHCID 86615363—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-c5dc5fad41474ca0be6fa143561f1f01
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)