Pyridine → 2-(4-fluorotetrahydro-2H-pyran-4-yl)-2-hydroxyacetonitrile
Reaction equation
[CH3:18][CH2:19][O:20][C:21](=[O:22])[CH3:23].[Cl:24][CH2:25][Cl:26].[FH:17].[O:1]1[CH:2]([C:9]#[N:10])[C:3]12[CH2:4][CH2:5][O:6][CH2:7][CH2:8]2.[n:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1>>[OH:1][CH:2]([C:3]1([F:17])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1)[C:9]#[N:10]Participants
6
Sources & evidence
- ORD record
- ord-c5dc5fad41474ca0be6fa143561f1f01
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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