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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 910210Generated: October 31, 2026

Potassium Carbonate → HCID 16735616, compound

https://huagongshe.com/reaction/910210

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantTosylmethyl isocyanideHCID 161915—
ReactantHCID 16738347HCID 16738347—
SolventMethanolHCID 887—
ProductHCID 16735616HCID 1673561645.9%

Reaction Steps

4-(6-Iodoimidazo[1,2-a]pyridin-2-yl)benzaldehyde (647 mg) and p-toluenesulfonylmethyl isocyanide (454 mg) were dissolved in methanol (10 mL), and potassium carbonate (321 mg) was added to the solution at room temperature, followed by refluxing for 13 hours. The precipitated product was recovered through filtration and dried, to thereby yield the title compound (330 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022075B2
Source datasetuspto-grants-2011_09
ORD IDord-566a10d1a880433c8a2abb72a75aa68c
Source noteuspto-grants-2011_09