Hydroxyamine hydrochloride → HCID 67403932, compound

Participants

Reaction Steps

Hydroxylamine hydrochloride (53 mg) was added to a solution (5 mL) of (E)-3-(dimethylamino)-1-[4-(6-iodoimidazo[1,2-a]pyridin-2-yl)phenyl]-2-propen-1-one (104 mg) in ethanol, followed by refluxing for 2 hours. The solvent was evaporated, and the residue was purified through silica gel chromatography (dichloromethane:methanol=97:3), to thereby yield the title compound (24 mg).

Provenance & Evidence