2-Amino-5-bromopyrimidine → 5-[4-(6-Bromoimidazo[1,2-a]pyrimidin-2-yl)phenyl]-1,3-oxazole

Participants

Reaction Steps

2-Amino-5-bromopyrimidine (348 mg) and 2-bromo-1-[4-(1,3-oxazol-5-yl)phenyl]-1-ethanone (532 mg) were suspended in 1,4-dioxane (20 mL), followed by refluxing under heating overnight. Immediately after refluxing, the reaction mixture was filtered without being cooled, followed by washing with heated 1,4-dioxane and drying, to thereby yield the title compound (587 mg).

Provenance & Evidence