HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chloropyridine → 5-[4-(6-Chloroimidazo[1,2-a]pyridin-2-yl)phenyl]-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chloropyridine | HCID 66174 | — |
| Reactant | 2-Bromo-1-[4-(1,3-oxazol-5-yl)phenyl]-1-ethanone | HCID 86631886 | — |
| Product | 5-[4-(6-Chloroimidazo[1,2-a]pyridin-2-yl)phenyl]-1,3-oxazole | HCID 25204119 | 27% |
Reaction Steps
The procedure of Referential Example 1 was repeated, except that 2-amino-5-chloropyridine (49 mg) and 2-bromo-1-[4-(1,3-oxazol-5-yl)phenyl]-1-ethanone (100 mg), which had been produced in Referential Example 10 were used, to thereby yield the title compound (30 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022075B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-3fcb4a2578e24390a13189413608667a |
| Source note | uspto-grants-2011_09 |