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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 910230Generated: October 31, 2026

Methyl 4-Formylbenzoate → Methyl 4-(1,3-oxazol-5-yl)benzoate

https://huagongshe.com/reaction/910230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-FormylbenzoateHCID 15294—
Reactant1-Isocyanatomethanesulfonyl-4-methylbenzeneHCID 11789078—
ProductMethyl 4-(1,3-oxazol-5-yl)benzoateHCID 147777986.7%

Reaction Steps

The procedure of Example 1 was repeated, except that methyl 4-formylbenzoate (4.92 g) and p-toluenesulfonylmethylisocyanate (7.03 g) were used, to thereby yield the title compound (5.28 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022075B2
Source datasetuspto-grants-2011_09
ORD IDord-8b746ed38abb4c5aba397f34fb336806
Source noteuspto-grants-2011_09