Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 910242Generated: October 29, 2026

2-Pyridinamine, 5-iodo- → HCID 67404368, compound

https://huagongshe.com/reaction/910242

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyridinamine, 5-iodo-HCID 88579—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 86761410HCID 86761410—
SolventEthanolHCID 702—
ProductHCID 67404368HCID 67404368—

Reaction Steps

Subsequently, 2-amino-5-iodopyridine (478 mg) and tert-butyl 4-[4-(2-bromoacetyl)phenyl]-1H-1-pyrazolecarboxylate mg) were dissolved in ethanol (20 mL), and sodium hydrogencarbonate (183 mg) was added to the solution, followed by refluxing for 16 hours. The precipitated matter was recovered through filtration and dried, to thereby yield the title compound (535 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022075B2
Source datasetuspto-grants-2011_09
ORD IDord-e5d440f8ce4e4ff68bbc7347f28c4e14
Source noteuspto-grants-2011_09