HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentane, 1-isocyanato- → methyl 2(S)-ethoxy-3-{4-[2-(1-methyl-3-pentylureido)thiazol-5-yl]phenyl}propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentane, 1-isocyanato- | HCID 206036 | — |
| Reactant | methyl 2(S)-ethoxy-3-[4-(2-methylaminothiazol-5-yl)phenyl]propanoate | HCID 86606239 | — |
| Product | methyl 2(S)-ethoxy-3-{4-[2-(1-methyl-3-pentylureido)thiazol-5-yl]phenyl}propanoate | HCID 67148249 | 26.1% |
Reaction Steps
In a manner similar to that of Example 71, starting with 0.17 g (0.53 mmol) of methyl 2(S)-ethoxy-3-[4-(2-methylaminothiazol-5-yl)phenyl]propionate and 0.14 ml (1.1 mmol) of pentyl isocyanate, 0.06 g (26%) of methyl 2(S)-ethoxy-3-{4-[2-(1-methyl-3-pentylureido)thiazol-5-yl]phenyl}propanoate is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022079B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-6bd7d5cf314b4c0792f7e5945b0ccca5 |
| Source note | uspto-grants-2011_09 |