HRID910334

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)O)c2)c1O$

HCID178433880

未命名化合物

PRODUCTS

生成物

$结构：CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)O)c2)c1O.NCCO$

HCID178433882

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6276

1-Pentanol

C5H12O

CONDITIONS

反应条件

温度: 70 °C

PROCEDURE

实验过程

Eltrombopag (15-20 mg) bisethanolamine was dissolved in 5 mL of 1-pentanol with heating to 70° C. and then was left to crystallize at 22° C. A precipitate formed and was separated by filtration and analysed. PXRD analysis provided the diffractogram as shown in FIG. 29.

WORKUP

后处理

waitwas left
customto crystallize at 22° C
customA precipitate formed
customwas separated by filtration
customPXRD analysis provided the diffractogram