Bromide ion → 1-[4-Chloro-3-(tetrahydro-pyran-2-yloxymethyl)-pyridin-2-yl]-ethanol
Reaction equation
[Br-:1].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:2][Mg+:3].[Cl:4][c:5]1[c:6]([CH2:13][O:14][CH:15]2[O:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[c:7]([CH:11]=[O:12])[n:8][cH:9][cH:10]1.[Na+:25].[O-:21][C:22]([OH:23])=[O:24]>>[Cl:4][c:5]1[c:6]([CH2:13][O:14][CH:15]2[O:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[c:7]([CH:11]([OH:12])[CH3:22])[n:8][cH:9][cH:10]1Participants
7
Sources & evidence
- ORD record
- ord-30c6e579ef7646d7a91afadb7121d2c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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