Hydrochloric Acid → HCID 57584092, compound

HRID 910612Notes

Reaction equation

HRID 910612 reaction equation
Cl.[O:2]=[C:3]1[C:8]([C:9]2[CH:18]=[CH:17][C:12]([C:13]([O:15]C)=[O:14])=[CH:11][CH:10]=2)=[CH:7][CH:6]=[CH:5][O:4]1>O>[O:2]=[C:3]1[C:8]([C:9]2[CH:18]=[CH:17][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=2)=[CH:7][CH:6]=[CH:5][O:4]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57584093HCID 57584093, compound

Product 1

HCID 57584092HCID 57584092, compoundYield 96.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
90 °C

Procedure

An aqueous 6 N hydrochloric acid solution (5 mL) was added to methyl 4-(2-oxo-2H-pyran-3-yl)benzoate (72 mg), followed by stirring at 90° C. for 15 hours. The reaction mixture was cooled to room temperature, water was added, and the solid was collected by filtration. After washing with water, this solid was dried under reduced pressure to obtain 4-(2-oxo-2H-pyran-3-yl)benzoic acid (65 mg) as a pale brown solid.

Workup

  1. temperatureThe reaction mixture was cooled to room temperature
  2. filtrationthe solid was collected by filtration
  3. washAfter washing with water
  4. customthis solid was dried under reduced pressure

Sources & evidence

ORD record
ord-3c993bb5180242b2ad2a5a947b7a5624
Source dataset
uspto-grants-2011_09
Patent number
US08022208B2

Reaction notes

Loading…