Phenylboronic Acid → HCID 25216954, compound

HRID 910696Notes

Reaction equation

HRID 910696 reaction equation
Br[C:2]1[S:6][C:5]([C:7]2[CH:12]=[C:11]([N:13]3[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]3)[CH:10]=[CH:9][N:8]=2)=[CH:4][CH:3]=1.[C:20]1(B(O)O)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH3:19][N:16]1[CH2:17][CH2:18][N:13]([C:11]2[CH:10]=[CH:9][N:8]=[C:7]([C:5]3[S:6][C:2]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:3][CH:4]=3)[CH:12]=2)[CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 25218410HCID 25218410, compound

Product 1

HCID 25216954HCID 25216954, compound

Procedure

The title compound was prepared by treating 1-[2-(5-bromo-thiophen-2-yl)-pyridin-4-yl]-4-methyl-piperazine with phenylboronic acid under conditions as described in Example 26.

Sources & evidence

ORD record
ord-16c939ac35cd45db983610c901042d79
Source dataset
uspto-grants-2011_09
Patent number
US08022209B2

Reaction notes

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