HCID 67061749, compound → HCID 67061875, compound

Participants

Reaction Steps

According to general procedure E, 1 mmol of [(2R,4R,5R)-4-[4-((S)-3-methoxy-2-methyl-propoxymethyl)-phenyl]-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulfonyl)-piperidin-2-ylmethyl]-carbamic acid benzyl ester is reacted in MeOH, to afford the title compound as a yellow oil. Rf=0.1 (CH2Cl2/MeOH/25% conc. NH3 200:10:1); Rt=4.62 (gradient I).

Provenance & Evidence