HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 3-Chloro-4-fluorophenyl methyl sulfide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-4-fluorobenzene-1-thiol | HCID 2734197 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Chloro-4-fluorophenyl methyl sulfide | HCID 55220709 | — |
Reaction Steps
Iodomethane (1.15 ml) was added to a stirred mixture of 3-chloro-4-fluoro-benzenethiol (3.0 g) and potassium carbonate (2.48 g) in DMF (20 ml) and left overnight. The reaction was diluted with water and extracted with diethylether, the organics were dried and evaporated under reduced pressure, yield 4.3 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022248B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-a3be6ec56249428aac1c9129a4c2c64c |
| Source note | uspto-grants-2011_09 |