HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → (2-(Benzyloxy)-4-fluorophenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 2-(Benzyloxy)-4-fluorobenzaldehyde | HCID 10680957 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2-(Benzyloxy)-4-fluorophenyl)methanol | HCID 58882932 | — |
Reaction Steps
Sodium borohydride (0.223 g) was added to a solution of the product from step (ii) (1.07 g) in dry ethanol (30 ml) and the mixture was stirred at RT overnight. The mixture was partitioned between 2M hydrochloric acid/ethyl acetate, the organics separated, dried and evaporated under reduced pressure, yield 1.08 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022248B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-653281e8ee7d42e08227a51e53a26612 |
| Source note | uspto-grants-2011_09 |