HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 58882949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | (2-(Benzyloxy)-4-fluorophenyl)methanol | HCID 58882932 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58882949 | HCID 58882949 | — |
Reaction Steps
A mixture of the product from step (iii) (1.06 g), methane sulphonyl chloride (0.351 ml) and triethylamine (0.636 ml) in DCM (20 ml) was stirred at RT for 2 h. The mixture was partitioned between water/DCM, the organics separated, dried and evaporated under reduced pressure. The residue was purified by chromatography on silica eluting with isohexane/DCM 1:1, yield 0.7 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022248B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-a74d5abf1c9a4a3393bc13c0b7a2e9eb |
| Source note | uspto-grants-2011_09 |