HCID 67390944, compound → HCID 67390729, compound

HRID 910853Notes

Reaction equation

HRID 910853 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8]C(=O)C)=[C:4]([O:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]3[N:23]=[C:22]([CH3:24])[O:21][N:20]=3)=[CH:15][C:14]=2[Cl:25])[CH:3]=1>Cl.C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([O:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]3[N:23]=[C:22]([CH3:24])[O:21][N:20]=3)=[CH:15][C:14]=2[Cl:25])[CH:3]=1

Participants

4

Reactant 1

HCID 67390944HCID 67390944, compound

Product 1

HCID 67390729HCID 67390729, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Procedure

The subtitle compound was prepared using the product from step ii) (0.50 g) which was dissolved in 2M HCl (10 ml) and ethanol (10 ml). The mixture was heated at reflux for 3 hours and concentrated under reduced pressure to an solid. Yield 0.45 g.

Workup

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 3 hours
  3. concentrationconcentrated under reduced pressure to an solid

Sources & evidence

ORD record
ord-244a1ba854d145dea089929695ed5538
Source dataset
uspto-grants-2011_09
Patent number
US08022248B2

Reaction notes

Loading…