3-Chlorothiophenol → HCID 63779018, compound

Participants

Reaction Steps

Using the method of Example 3, Step A, 3-chlorobenzenethiol (912 mg, 6.31 mmol), 60% sodium hydride in mineral oil (252 mg, 6.31 mmol), and 2-chloro-4-nitropyridine (1.00 g, 6.31 mmol) were reacted to afford 2-chloro-4-(3-chlorophenylthio)pyridine (1.48 g, 92% yield) as an oil. 1H NMR (CDCl3) δ 8.16 (d, 1H), 7.56 (s, 1H), 7.39-7.49 (m, 3H), 6.94 (s, 1H), 6.88 (d, 1H).

Provenance & Evidence