Sodium Hydroxide → HCID 86634746, compound

Participants

Reaction Steps

A mixture of N-(5-bromo-4-(2,6-difluorophenoxy)pyridin-2-ylcarbamothioyl)benzamide (4.41 g, 9.5 mmol) and 3M NaOH (10 ml, 30 mmol) in ethanol (40 mL) is heated. The reaction mixture is cooled, concentrated to 15 mL, diluted with water, and filtered to afford 1-(5-bromo-4-(2,6-difluorophenoxy)pyridin-2-yl)thiourea.

Provenance & Evidence