Sodium Hydroxide → HCID 86634748, compound

Participants

Reaction Steps

A mixture of N-(5-bromo-3-chloro-4-(2,6-difluorophenoxy)pyridin-2-ylcarbamothioyl)benzamide (474 mg, 0.95 mmol) and 3M NaOH (1 mL, 30 mmol) in ethanol (4 mL) is heated. The reaction mixture is cooled, concentrated to 2 mL, diluted with water, and filtered to afford 1-(5-bromo-3-chloro-4-(2,6-difluorophenoxy)pyridin-2-yl)thiourea.

Provenance & Evidence