HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Bromomethyl)-6-chloropyridazine → HCID 19040625, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Bromomethyl)-6-chloropyridazine | HCID 23080925 | — |
| Reactant | 3-tert-butoxycarbonyl-7-chloro-6-dimethylaminocarbonylthio-2,3,4,5-tetrahydro-1H-benzo[d]azepine | HCID 57655979 | — |
| Product | HCID 19040625 | HCID 19040625 | — |
Reaction Steps
Use a method similar to the Preparation 177, using 3-tert-butoxycarbonyl-7-chloro-6-dimethylcarbamoylthio-2,3,4,5-tetrahydro-1H-benzo[d]azepine and 3-bromomethyl-6-chloropyridazine to give 3-tert-butoxycarbonyl-7-chloro-6-(6-chloro-pyridazin-3-ylmethylthio)-2,3,4,5-tetrahydro)-1H-benzo[d]azepine. Use a method similar to the General Procedure 14 to give the title compound as an off-white powder. MS (APCI+) m/z: 340 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022062B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-62c678f9c7254a75a34bab832e882256 |
| Source note | uspto-grants-2011_09 |