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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 911993Generated: October 31, 2026

Hydrochloric Acid → HCID 57812685, compound

https://huagongshe.com/reaction/911993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57812632HCID 57812632—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
ProductHCID 57812685HCID 57812685—

Reaction Steps

To a solution of 4-(4-{6-amino-2-bromo-7-[(R)-1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-furo[3,2-c]pyridin-3-yl}-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester (2.0 mg, 0.0030 mmol) in DCM (0.1 mL) was added 1N HCl in diethyl ether (0.2 mL). The resulting mixture was stirred at rt overnight. Evaporation afforded the title compound as a light-yellow gum. LC-MS (ES+): 567.97/569.97/571.99 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022206B2
Source datasetuspto-grants-2011_09
ORD IDord-1dee32a3aac74c4186378b730e539c41
Source noteuspto-grants-2011_09