HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 57812685, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 57812632 | HCID 57812632 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57812685 | HCID 57812685 | — |
Reaction Steps
To a solution of 4-(4-{6-amino-2-bromo-7-[(R)-1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-furo[3,2-c]pyridin-3-yl}-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester (2.0 mg, 0.0030 mmol) in DCM (0.1 mL) was added 1N HCl in diethyl ether (0.2 mL). The resulting mixture was stirred at rt overnight. Evaporation afforded the title compound as a light-yellow gum. LC-MS (ES+): 567.97/569.97/571.99 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022206B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-1dee32a3aac74c4186378b730e539c41 |
| Source note | uspto-grants-2011_09 |