HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 57812300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 57812667 | HCID 57812667 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57812300 | HCID 57812300 | — |
Reaction Steps
To a solution of 4-({6-amino-7-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridine-3-carbonyl}-amino)-piperidine-1-carboxylic acid tert-butyl ester (6.0 mg, 0.01 mmol) in DCM (0.2 mL) was added 1M HCl in Et2O (0.5 mL). The resulting mixture was stirred at rt overnight. LC-MS showed the reaction was complete and gave the desired product. Evaporation under reduced gave the title compound as a white solid. LC-MS (ES+): 467.00/469.04 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022206B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-d291fa0223ad491099dca25535af4783 |
| Source note | uspto-grants-2011_09 |