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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 911997Generated: October 28, 2026

Hydrochloric Acid → HCID 57812300, compound

https://huagongshe.com/reaction/911997

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57812667HCID 57812667—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
ProductHCID 57812300HCID 57812300—

Reaction Steps

To a solution of 4-({6-amino-7-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridine-3-carbonyl}-amino)-piperidine-1-carboxylic acid tert-butyl ester (6.0 mg, 0.01 mmol) in DCM (0.2 mL) was added 1M HCl in Et2O (0.5 mL). The resulting mixture was stirred at rt overnight. LC-MS showed the reaction was complete and gave the desired product. Evaporation under reduced gave the title compound as a white solid. LC-MS (ES+): 467.00/469.04 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022206B2
Source datasetuspto-grants-2011_09
ORD IDord-d291fa0223ad491099dca25535af4783
Source noteuspto-grants-2011_09