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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912088Generated: October 31, 2026

4-(Trifluoromethoxy)aniline → HCID 59244508, compound

https://huagongshe.com/reaction/912088

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
Reactant4-[4-Chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]morpholineHCID 59244988—
ReactantHCID 67385473HCID 67385473—
ProductHCID 59244508HCID 59244508—

Reaction Steps

In the same manner as Example 1-A-01, from 4-[4-chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]-morpholine and 4-trifluoromethoxyaniline, 4-(3-methoxy-phenyl)-2-morpholin-4-yl-7-(4-trifluoromethoxy-phenyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine was obtained, and subsequently, further in the same manner as Example 1-A-09, the desired compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022205B2
Source datasetuspto-grants-2011_09
ORD IDord-6510e9377dd442318e763c4701c5358a
Source noteuspto-grants-2011_09