HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boronic Acid → HCID 24890443, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boronic Acid | HCID 61668 | — |
| Reactant | 2-Methoxypyrimidine-5-boronic acid | HCID 2736778 | — |
| Reactant | 4-chloro-2-morpholin-4-yl-7-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine | HCID 59244708 | — |
| Product | HCID 24890443 | HCID 24890443 | — |
Reaction Steps
In the same manner as Example 1-B-10, using 4-chloro-2-morpholin-4-yl-7-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine, and 2-methoxypyrimidin-5-boronic acid as a boronic acid, 4-(2-methoxy-pyrimidin-5-yl)-2-morpholin-4-yl-7-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine was obtained. This was demethylated in the same manner as Example 1-B-42, to obtain the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022205B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-8f36eea9c4824ea19f5d72636084da46 |
| Source note | uspto-grants-2011_09 |