HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 57736564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 3-tert-Butyloxycarbonylamino-2-piperidone | HCID 124787 | — |
| Product | HCID 57736564 | HCID 57736564 | — |
Reaction Steps
(S)-tert-butyl 1-methyl-2-oxopiperidin-3-ylcarbamate was prepared from (S)-tert-butyl 2-oxopiperidin-3-ylcarbamate (Example 7) and methyl iodide according to the general procedure of Example 9. The crude product was purified by column chromatography, eluting with 100% ethyl acetate, to provide compound (2c) in 31% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026233B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-93fcb1fc4a7146308502edf4c1dae0e2 |
| Source note | uspto-grants-2011_09 |