Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912686Generated: October 30, 2026

Ammonia → HCID 62846302, compound

https://huagongshe.com/reaction/912686

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-(Aminomethyl)-5-methylpyrazineHCID 2756496—
SolventMethanolHCID 887—
ProductHCID 62846302HCID 6284630291%

Reaction Steps

The title compound was prepared in accordance with the general method described in Example 12(a) by using 2-(aminomethyl)-5-methylpyrazine (1.00 g, 7.89 mmol), benzoyl isothiocyanate (1.20 mL, 8.90 mmol) and ammonia in methanol (7 N, 27 mL) with the exception that the crude product isolated by filtration (1.30 g, 91% yield) was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026244B2
Source datasetuspto-grants-2011_09
ORD IDord-ae90332c31d94c9a8d95bbdf234d9601
Source noteuspto-grants-2011_09