HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 86631134, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | (4-Methyl-1,2,5-oxadiazol-3-yl)methanamine | HCID 565861 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86631134 | HCID 86631134 | 78% |
Reaction Steps
The title compound was prepared in accordance with the general method described in Example 12(a) by using 1-(4-methyl-1,2,5-oxadiazol-3-yl)methylamine (0.46 g, 4.1 mmol), benzoyl isothiocyanate (0.60 mL, 4.5 mmol) and ammonia in methanol (7 N, 25 mL) with the exception that the crude product isolated by filtration (0.55 g, 78% yield) was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026244B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-d3d3b0236bf34d28985288871a35cc95 |
| Source note | uspto-grants-2011_09 |