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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912693Generated: October 31, 2026

Ammonia → HCID 86631134, compound

https://huagongshe.com/reaction/912693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant(4-Methyl-1,2,5-oxadiazol-3-yl)methanamineHCID 565861—
SolventMethanolHCID 887—
ProductHCID 86631134HCID 8663113478%

Reaction Steps

The title compound was prepared in accordance with the general method described in Example 12(a) by using 1-(4-methyl-1,2,5-oxadiazol-3-yl)methylamine (0.46 g, 4.1 mmol), benzoyl isothiocyanate (0.60 mL, 4.5 mmol) and ammonia in methanol (7 N, 25 mL) with the exception that the crude product isolated by filtration (0.55 g, 78% yield) was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026244B2
Source datasetuspto-grants-2011_09
ORD IDord-d3d3b0236bf34d28985288871a35cc95
Source noteuspto-grants-2011_09