HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl cyanoacetate → HCID 86631135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | HCID 86631134 | HCID 86631134 | — |
| Product | HCID 86631135 | HCID 86631135 | 58% |
Reaction Steps
The title compound was prepared in accordance with the general method described in Example 12(b) by using 1-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]thiourea (0.55 g, 3.2 mmol, obtained from Example 16(a)), sodium ethoxide (21% w/v, 3.1 mL, 9.5 mmol) and ethyl cyanoacetate (1.0 mL, 9.5 mmol) which provided the title compound (0.44 g, 58% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026244B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-bca56a5d3dda4f04882bb5206987f75c |
| Source note | uspto-grants-2011_09 |