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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912694Generated: October 31, 2026

Ethyl cyanoacetate → HCID 86631135, compound

https://huagongshe.com/reaction/912694

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl cyanoacetateHCID 7764—
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 86631134HCID 86631134—
ProductHCID 86631135HCID 8663113558%

Reaction Steps

The title compound was prepared in accordance with the general method described in Example 12(b) by using 1-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]thiourea (0.55 g, 3.2 mmol, obtained from Example 16(a)), sodium ethoxide (21% w/v, 3.1 mL, 9.5 mmol) and ethyl cyanoacetate (1.0 mL, 9.5 mmol) which provided the title compound (0.44 g, 58% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026244B2
Source datasetuspto-grants-2011_09
ORD IDord-bca56a5d3dda4f04882bb5206987f75c
Source noteuspto-grants-2011_09