HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl [(phenoxycarbonyl)oxy]acetate → 2-(Ethyloxy)-2-oxoethyl 4-{2-[(4-bromophenyl)oxy]ethyl}-1-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl [(phenoxycarbonyl)oxy]acetate | HCID 12094709 | — |
| Reactant | 4-{2-[(4-Bromophenyl)oxy]ethyl}-piperidine | HCID 56830278 | — |
| Product | 2-(Ethyloxy)-2-oxoethyl 4-{2-[(4-bromophenyl)oxy]ethyl}-1-piperidinecarboxylate | HCID 67415025 | 54.6% |
Reaction Steps
The procedure described in Example 4.3. is repeated. Starting from 1.76 g (6.19 mmol) of 4-{2-[(4 bromophenyl)oxy]ethyl} prepared in Step 9.2., and 1.39 g (6.19 mmol) of ethyl{[(phenyloxy)carbonyl]oxy}-acetate, prepared in accordance with Example 1.1., gives 1.4 g of product in oil form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026258B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-5322c33b4e1d4ae89a8e6cd29b527c1c |
| Source note | uspto-grants-2011_09 |