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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912824Generated: November 1, 2026

2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole → HCID 178486270, compound

https://huagongshe.com/reaction/912824

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazoleHCID 11638867—
Reactant2-Piperazin-1-yl-pyridine-3-sulfonic acid methylamideHCID 67401356—
ProductHCID 178486270HCID 178486270—

Reaction Steps

The piperazine from step (a) above (128 mg, 0.5 mmol) reacted with 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole (140 mg, 0.4 mmol, Example 51b) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 571 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026241B2
Source datasetuspto-grants-2011_09
ORD IDord-b1b2e67a5f2f42ad998211a253cb8bf9
Source noteuspto-grants-2011_09