HuagongsheHuagongshe Chemistry Print Report · For research reference only
{5-Chloro-6-[(3R)-3-methylpiperazin-1-yl]pyridin-3-yl}methanol → HCID 178461541, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {5-Chloro-6-[(3R)-3-methylpiperazin-1-yl]pyridin-3-yl}methanol | HCID 11550484 | — |
| Reactant | 1H-Benzimidazole, 2-chloro-7-iodo-5-(trifluoromethyl)- | HCID 67401406 | — |
| Product | HCID 178461541 | HCID 178461541 | — |
Reaction Steps
The piperazine from step (a) above (73 mg, 0.3 mmol) reacted with 2-chloro-4-iodo-6-(trifluoromethyl)-1H-benzoimidazole (69 mg, 0.2 mmol, Example 61c) under the conditions of Example 3c to give the title compound as a yellow amorphous solid. MS (ESI, pos. ion) m/z: 552 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-30da44ed59eb4175b6d764cab7274123 |
| Source note | uspto-grants-2011_09 |