HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperazine, (S)- → HCID 178461509, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperazine, (S)- | HCID 2734219 | — |
| Reactant | 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole | HCID 11638867 | — |
| Product | HCID 178461509 | HCID 178461509 | — |
Reaction Steps
2-Chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole (350 mg, 1 mmol, Example 51b) reacted with (S)-(+)-2-methylpiperazine (150 mg. 1.5 mmol, Aldrich) under the conditions of Example 3c to give the title compound as a light-brown solid. MS (ESI, pos. ion) m/z: 415 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-4d285dc1591f4c0e9bc22b59c8f4d6e2 |
| Source note | uspto-grants-2011_09 |