HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminomethylphenylboronic acid hydrochloride → HCID 178509570, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminomethylphenylboronic acid hydrochloride | HCID 2734311 | — |
| Reactant | 4-Bromo-6-trifluoromethyl-2-[4-(3-trifluoromethylpyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole | HCID 11670445 | — |
| Product | HCID 178509570 | HCID 178509570 | — |
Reaction Steps
The title compound was prepared from 4-bromo-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1H-benzoimidazole (Example 7) and 4-aminomethylphenylboronic acid hydrochloride (Acros) under the conditions of Example 51a and isolated as a white amorphous solid. MS (ESI, pos. ion) m/z: 521 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-b1607349cff4488d81a1c107dd308bd2 |
| Source note | uspto-grants-2011_09 |