Cyclopentylamine → 4-(2-chloro-4-pyridinyl)-N-cyclopentyl-2-pyrimidinamine

Participants

Reaction Steps

Cyclopentylamine (3 mL) was combined with 2-chloro-4-(2-chloro-4-pyridinyl)pyrimidine (i.e., the product of Example 6, Step A) (300 mg, 1.3 mmol) and stirred at 55° C. for 2 hours. The resulting suspension was filtered, and the collected solid was oven dried at 50° C. in vacuo to give 340 mg of the title compound as a brown solid.

Provenance & Evidence